Dr. Cara Flamer – BioIdentical Hormone Therapy

The Role of Hormones in Anxiety and Emotional Wellbeing

Much of what I have learned about hormones comes from my post–medical school training in integrative medicine. One observation that stands out from working with women in this field is how frequently anxiety is discussed in relation to hormonal imbalance.

Anxiety is something many people experience at different points in life. It may appear during stressful periods, life transitions, or times of emotional difficulty. In some cases, the source of anxiety feels clear, while in others it may be harder to identify, which can add to feelings of uncertainty or frustration. When anxiety begins to interfere with sleep, work, or relationships, additional support may be helpful.

In my experience, anxiety is often discussed in connection with two overlapping physiological patterns:

Stress-related hormone patterns

Stress hormones play an important role in how the body responds to ongoing demands. When stress is prolonged, people may notice symptoms such as feeling “wired but tired,” difficulty unwinding, disrupted sleep, increased irritability, or a tendency to crash during periods of rest. These patterns can influence emotional balance over time.

Sex hormone patterns

Hormones such as progesterone and estrogen are commonly discussed in relation to mood and emotional regulation. Changes in these hormones—whether related to stress, life stage, or menstrual irregularity—may be associated with symptoms such as disrupted sleep, mood changes, irritability, or heightened emotional sensitivity.

These two patterns are often interconnected. Prolonged stress can influence cortisol levels, which in turn may affect other hormones and neurotransmitters involved in emotional regulation. This interaction helps explain why emotional symptoms may emerge or intensify during periods of sustained stress or hormonal transition.

Supportive approaches

There are a variety of supportive strategies that may be explored when anxiety is discussed alongside hormonal patterns. These may include stress-management practices, lifestyle adjustments, nutritional support, and, when appropriate, working with a qualified healthcare practitioner to assess hormone balance more closely.

It is important to note that experiences with anxiety vary widely. What is helpful for one person may not be appropriate for another, and a personalized approach is often most supportive.

If anxiety becomes overwhelming, persistent, or significantly interferes with daily functioning, seeking guidance from a medical professional is essential.

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